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Photograph of woman applying progesterone lotion to skin

Progesterone Dosing Recommendation

Progesterone cream usually does not require a prescription to purchase and because of this there are many different progesterone products on the market. But not all progesterone creams are created equal. Independent studies have revealed that OTC progesterone creams vary widely in potency and their ability to be absorbed.

It is important to make sure you use a quality progesterone product that has an accurate dosing method and that has been tested to ensure potency. This can be an overwhelming endeavor. The good news is that we have done the work for you.

The brand of Progesterone Cream that we are selling at Collier Compounding is Serenity Progesterone Cream.

Each pump delivers 15mg of Progesterone. Each airless dispensing system contains 90 doses.Serenity Progest Crm

Dosing Guidelines

Note: Day 1 of your cycle is the first day of your period.

Premenstrual Syndrome: Apply 1 pump (15 mg) topically on days 14 through 25 of cycle

Peri-Menopausal: Apply 1 to 2 pumps (15 to 30mg) topically on days 14 through 25 of cycle

Migraines: Apply 1 pump (15 mg) once or twice daily for 10 days prior to start of menstruation. If aura begins, you can apply 1 pump to base of neck every 3 hours for up to 2 doses.

Fibrocystic Breasts: Apply 1 pump (15 mg) twice daily from day 10 through day 23 of cycle

Menopausal: Apply 1 to 2 pumps (15 to 30mg) once daily. It may take up to 3 months of consistent dosing to restore the balance between progesterone and estrogen.

Application of Progesterone Cream

Progesterone cream is typically applied to upper inner arms, inner thighs, and inner forearm. The idea is to have an area with thin enough skin for the Progesterone to absorb through easily. Progesterone is also fat soluble, so these areas typically have enough tissue around them to ensure good absorption. Alternate the sites of application. This will allow for more consistent absorption. Make sure you rub the cream in well – ideally 1 minute.

Caution should be taken to prevent transference of the Progesterone Cream to others, including children and pets. To help avoid transference, wash your hands immediately after apply the cream. Allow 2 hours for the cream to fully dry before anyone comes in contact with that area of skin.

Do not take natural Progesterone and Medroxyprogesterone (Provera or Depo-Provera) at the same time.

Want to Learn More?

Pick up one of these books by Dr. John Lee at Collier Compounding for a more detailed look at hormones and how they affect YOU!