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How do I take my Thyroid Medicine?

By: Julie Cole, Pharm.D.

The key to getting the best absorption of your thyroid medication is consistency; otherwise, there will be erratic absorption, and it will be harder to regulate your thyroid levels.

When should I take my thyroid medicine?

The ideal time to take your thyroid medication is in the morning on an empty stomach about one hour before eating because food delays the drugs absorption.  An alternative for those whose schedules do not allow this may try taking it at night before bedtime.  In order to achieve consistent levels one has to create a routine that is the same each day because small changes can make a big difference in keeping your thyroid healthy.

What can affect my thyroid absorption?


One in particular that we are all familiar with is caffeine. It is recommended that you wait an hour after your morning coffee before taking your thyroid medication.


Antacids like Tums, Rolaids, or Mylanta should not be taken within 2 hours of your thyroid medication.

Cold & Cough Medicine

There is usually a warning on cough and cold medications that reads you should not take if you have thyroid disease.  The logic behind this is for those who have hyperthyroidism. One never wants to add an additional stimulant such as pseudoephedrine, and for those who have hypothyroidism these medications need to be taken with caution and I would recommend starting with a partial dose to see if your body is sensitive and talking to your physician.

There are many factors that can affect your thyroid medications, and we are always ready to provide our services to answer your questions.

If you have a specific question, you can utilize our “Ask a Pharmacist” service where you will get a timely answer from one of our excellent pharmacists on staff.  You can also ask about our custom thyroid options from one of our pharmacists at our Collier Compounding lab.